Description

Butyryl-L-Carnitine-D3 (Chloride) is a high-purity, isotopically labeled derivative of L-carnitine, specifically designed for advanced research and development applications. This compound is critical for metabolic studies, serving as a stable internal standard in mass spectrometry to ensure accurate quantification and traceability. It is primarily utilized by pharmaceutical R&D teams, clinical research organizations, and analytical laboratories focused on lipid metabolism, biomarker discovery, and pharmacokinetic studies.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the precise quantification of L-carnitine and its esters in biological matrices like plasma, serum, and tissue homogenates.
• Metabolic Pathway Research: Facilitates tracer studies to investigate fatty acid β-oxidation, mitochondrial function, and energy metabolism in preclinical models.
• Biomarker Analysis: Enables the development of highly sensitive and specific diagnostic assays for metabolic disorders, including primary and secondary carnitine deficiencies.
• Pharmaceutical Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies for candidate drugs targeting metabolic pathways.
• Nutraceutical & Sports Science Research: Supports studies on the efficacy, absorption, and distribution of carnitine-based dietary supplements.
• Quality Control Reference: Serves as a certified reference material (CRM) for calibrating analytical instruments and validating methods in quality control laboratories.

Basic Information

Product Name	Butyryl-L-Carnitine-D3 (Chloride)
CAS No.	1334532-21-6
Molecular Formula	C11H17D3ClNO4
Molecular Weight	262.75 g/mol (for monoisotopic mass)
Synonyms	L-Butyrylcarnitine-d3 chloride; (3R)-3-[(Butanoyl-d3)oxy]-4-(trimethylammonio)butanoate Chloride; O-Butanoyl-d3-L-carnitine Chloride; Butyryl-L-carnitine-d3 HCl; Deuterated Butyryl-L-carnitine Chloride; Butyrylcarnitine-d3 (Chloride Salt); 3-Butyryloxy-4-trimethylaminobutyrate-d3 Chloride
EINECS	Contact for details

Quality Control

Our Butyryl-L-Carnitine-D3 (Chloride) is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced analytical techniques including NMR, HPLC, and mass spectrometry. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium, D)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.