Description

tert-Butyl 4-[(Pyridin-4-Yl)Carbonyl]Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core functionalized with a pyridinyl carbonyl group and protected by a tert-butyloxycarbonyl (Boc) moiety. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Used in multi-step organic synthesis to introduce the 4-(pyridine-4-carbonyl)piperidine fragment into more complex molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for the study of heterocyclic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	tert-Butyl 4-[(Pyridin-4-Yl)Carbonyl]Piperidine-1-Carboxylate
CAS No.	1334415-27-8
Molecular Formula	C16H22N2O3
Molecular Weight	290.36 g/mol
Synonyms	1-Boc-4-(pyridine-4-carbonyl)piperidine; 1-(tert-Butoxycarbonyl)-4-(4-pyridinylcarbonyl)piperidine; 4-(Pyridine-4-carbonyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4-pyridylcarbonyl)piperidine-1-carboxylate; 1-Boc-4-(isonicotinoyl)piperidine; 4-(Isonicotinoyl)piperidine-1-carboxylic acid tert-butyl ester; BOC-4-Pyridin-4-ylcarbonyl-piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(Pyridin-4-Yl)Carbonyl]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.