Description

3-Fluoro-4-((4-Methylpiperazin-1-Yl)Methyl)Phenylboronic Acid is a high-value, synthetically versatile boronic acid derivative that serves as a critical building block in modern organic synthesis. Its core value proposition lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, particularly the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require advanced intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boronic acid coupling partner for forming carbon-carbon bonds between aromatic rings, a fundamental step in creating complex biaryl structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and piperazine motifs can contribute to biological activity and metabolic stability.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and fluorescent molecules for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Synthesis: Useful for creating molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Fluoro-4-((4-Methylpiperazin-1-Yl)Methyl)Phenylboronic Acid
CAS No.	1334401-01-2
Molecular Formula	C12H18BFN2O2
Molecular Weight	252.10 g/mol
Synonyms	[3-Fluoro-4-[(4-Methyl-1-piperazinyl)methyl]phenyl]boronic Acid; (3-Fluoro-4-((4-methylpiperazin-1-yl)methyl)phenyl)boronic Acid; 3-Fluoro-4-[(4-methylpiperazin-1-yl)methyl]benzeneboronic Acid; Boronic acid, B-[3-fluoro-4-[(4-methyl-1-piperazinyl)methyl]phenyl]-; 3-Fluoro-4-(4-methylpiperazine-1-ylmethyl)phenylboronic Acid; 1334401-01-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-((4-Methylpiperazin-1-Yl)Methyl)Phenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, and our quality system is designed to support regulatory filings for our customers in advanced markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.