Description

Sulfadimethoxine-13C6 is a stable isotope-labeled analog of the veterinary antibiotic sulfadimethoxine, where six carbon atoms are replaced with the carbon-13 isotope. This compound is essential as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reliability in analytical measurements. It is critically needed by research laboratories, pharmaceutical companies, and contract research organizations (CROs) engaged in drug metabolism studies, residue testing, and high-precision bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Primary use as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for veterinary drug analysis.
• Drug Metabolism and Pharmacokinetics (DMPK): Enables precise tracking and quantification of sulfadimethoxine and its metabolites in biological matrices during ADME studies.
• Veterinary Residue Testing: Critical for ensuring food safety by accurately measuring sulfadimethoxine residues in meat, milk, eggs, and honey to comply with maximum residue limits (MRLs).
• Bioanalytical Method Development & Validation: Used to develop, optimize, and validate robust, regulatory-compliant analytical methods (e.g., following FDA/EMA guidelines).
• Clinical Research: Supports pharmacokinetic studies in animals to determine accurate drug concentration profiles.
• Quality Control & Assurance: Serves as a critical component in the quality control protocols of analytical laboratories and manufacturers.

Basic Information

Product Name	Sulfadimethoxine-13C6
CAS No.	1334378-48-1
Molecular Formula	13C6C6H14N4O4S
Molecular Weight	~314.31 (based on 13C substitution)
Synonyms	4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl-13C6)benzenesulfonamide; Sulfadimethoxine (13C6); 13C6-Sulfadimethoxine; Sulfadimethoxine-13C6 Internal Standard; [13C6]-Sulfadimethoxine; Sulfadimethoxine (carbon-13 labeled); SDM-13C6; Stable Isotope-Labeled Sulfadimethoxine
EINECS	Contact for details

Quality Control

Our Sulfadimethoxine-13C6 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (atom % 13C), chemical purity (by HPLC), and identity confirmation (by NMR and MS). We support compliance with GMP/GLP principles for research and regulatory submission purposes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥99 atom % 13C
Chemical Purity	≥95%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.