Description

Sulfafurazole-13C6 is a stable isotope-labeled analog of the sulfonamide antibiotic sulfafurazole, where six carbon atoms are replaced with the 13C isotope. This compound is an essential internal standard for the precise and accurate quantification of sulfafurazole in complex matrices using advanced analytical techniques like LC-MS/MS. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and residue testing.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical internal standard for the quantitative analysis of sulfafurazole in biological samples (plasma, serum, urine) via LC-MS/MS, ensuring data accuracy and compensating for instrument variability.
• Drug Metabolism Studies (DMPK): Used in pharmacokinetic and metabolic stability studies to track the parent drug and its metabolites, facilitating ADME (Absorption, Distribution, Metabolism, Excretion) profiling.
• Bioanalytical Method Development & Validation: Essential for developing and validating robust, regulatory-compliant (FDA, EMA) bioanalytical assays for sulfafurazole quantification.
• Veterinary Drug Residue Analysis: Applied in food safety testing to monitor and quantify sulfafurazole residues in animal-derived food products to ensure compliance with maximum residue limits (MRLs).
• Clinical Research: Supports therapeutic drug monitoring (TDM) and clinical trial sample analysis where precise measurement of sulfafurazole concentrations is required.
• Environmental Fate Studies: Aids in tracing the environmental persistence and breakdown pathways of sulfonamide antibiotics in ecological samples.

Basic Information

Product Name	Sulfafurazole-13C6
CAS No.	1334378-46-9
Molecular Formula	¹³C₆C₅H₁₃N₃O₃S
Molecular Weight	~271.3 g/mol (exact mass varies with isotopic enrichment)
Synonyms	13C6-Sulfafurazole; Sulfisoxazole-13C6; 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)-13C6-benzenesulfonamide; 5-(p-Aminophenylsulfonamido)-3,4-dimethylisoxazole-13C6; N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide-13C6; Isotopically Labeled Sulfafurazole; Sulfafurazole (13C6); [13C6]-Sulfisoxazole
EINECS	Contact for details

Quality Control

Every batch of Sulfafurazole-13C6 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization by NMR, MS, and HPLC. Certificates of Analysis (COA) are provided for each lot, detailing the isotopic enrichment (atom % 13C), chemical purity, and results of all identity and purity tests. Our quality commitment ensures reliability for your most demanding analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (atom % 13C)	≥99% on the labeled positions
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.