Description

3-Fluoro-4-((4-Methylpiperidin-1-yl)methyl)phenylboronic Acid is a high-value, synthetically versatile organoboron building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures containing the 3-fluoro-4-(aminomethyl)phenyl pharmacophore.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used to create novel herbicide and fungicide candidates by introducing specific fluorinated aromatic motifs.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and liquid crystals.
• Chemical Biology & Probe Development: Enables the labeling and study of biological targets through bioconjugation strategies.
• Catalyst Ligand Synthesis: Employed in the preparation of sophisticated ligand systems for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Essential for CROs and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	3-Fluoro-4-((4-Methylpiperidin-1-yl)methyl)phenylboronic Acid
CAS No.	1334321-25-3
Molecular Formula	C13H19BFNO2
Molecular Weight	251.11 g/mol
Synonyms	[3-Fluoro-4-[(4-methyl-1-piperidinyl)methyl]phenyl]boronic Acid; 3-Fluoro-4-((4-methylpiperidin-1-yl)methyl)benzeneboronic Acid; 3-Fluoro-4-[(4-methylpiperidin-1-yl)methyl]phenylboronic Acid; 1334321-25-3; B-[3-Fluoro-4-[(4-methyl-1-piperidinyl)methyl]phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-((4-Methylpiperidin-1-yl)methyl)phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.