Description

Boronic Acid, B-[3-[[3-(Trifluoromethyl)Phenyl]Methoxy]Phenyl]- is a specialized aryltrifluoromethyl-substituted boronic acid derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, particularly the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, where the trifluoromethyl group is a key motif for enhancing metabolic stability and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in constructing advanced herbicides, fungicides, and insecticides where the CF3 group improves biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for synthesizing organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura palladium-catalyzed cross-couplings to form biaryl and heterobiaryl structures with high efficiency and selectivity.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for studying biological processes and protein interactions.
• Ligand and Catalyst Development: Acts as a building block for creating novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Boronic Acid, B-[3-[[3-(Trifluoromethyl)Phenyl]Methoxy]Phenyl]-
CAS No.	1334307-13-9
Molecular Formula	C14H12BF3O3
Molecular Weight	296.05 g/mol
Synonyms	[3-[[3-(Trifluoromethyl)phenoxy]phenyl]boronic acid; (3-((3-(Trifluoromethyl)phenoxy)phenyl)boronic acid; 3-((3-(Trifluoromethyl)phenoxy)benzeneboronic acid; B-[3-[[3-(Trifluoromethyl)Phenyl]Methoxy]Phenyl]Boronic Acid; 3-(3-Trifluoromethylphenoxy)phenylboronic acid; Boronic acid, B-[3-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]-; 1334307-13-9
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[3-[[3-(Trifluoromethyl)Phenyl]Methoxy]Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.