Description

4-(Ethoxymethyl)-3-Fluorophenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecular architectures through reliable cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorinated phenyl ring contributes to enhanced biological activity and metabolic stability.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client R&D pipelines.

Basic Information

Product Name	4-(Ethoxymethyl)-3-Fluorophenylboronic Acid
CAS No.	1334218-48-2
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	3-Fluoro-4-(ethoxymethyl)benzeneboronic Acid; (3-Fluoro-4-(ethoxymethyl)phenyl)boronic Acid; 4-(Ethoxymethyl)-3-fluorobenzeneboronic Acid; B-[3-Fluoro-4-(ethoxymethyl)phenyl]boronic Acid; 3-Fluoro-4-ethoxymethylphenylboronic Acid; 1334218-48-2; Boronic acid, B-[3-fluoro-4-(ethoxymethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 4-(Ethoxymethyl)-3-Fluorophenylboronic Acid is produced and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard grade meets the stringent requirements for advanced research and process development, with specifications tailored to support cGMP (current Good Manufacturing Practice) workflows where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.