Description

Lissamine Rhodamine B Sulfonamide-Dpeg4-Acid(Chloride) is a high-purity, reactive fluorescent labeling reagent designed for advanced bioconjugation and probe synthesis. This compound is critical for researchers and manufacturers requiring stable, bright, and water-soluble fluorescent tags for biomolecules. It is primarily needed by professionals in biotechnology, pharmaceutical R&D, and diagnostic assay development for creating sensitive detection systems.

Application

• Fluorescent Labeling of Biomolecules: Covalent conjugation to antibodies, peptides, proteins, and oligonucleotides for imaging and detection.
• Diagnostic Assay Development: Synthesis of fluorescent probes and tracers for ELISA, lateral flow assays, and in vitro diagnostics (IVD).
• Live-Cell and Tissue Imaging: Preparation of cell-permeable probes for fluorescence microscopy and flow cytometry applications.
• Chemical Biology & Proteomics: Tool compound for activity-based protein profiling (ABPP) and target engagement studies.
• Polymer & Material Science: Functionalization of nanoparticles, hydrogels, and polymeric materials with a fluorescent moiety.
• Drug Delivery & Pharmacokinetics: Tracing and visualization of drug conjugates and delivery vehicles in preclinical research.

Basic Information

Product Name	Lissamine Rhodamine B Sulfonamide-Dpeg4-Acid(Chloride)
CAS No.	1334177-85-3
Molecular Formula	C52H67ClN4O11S2
Molecular Weight	1043.7 g/mol
Synonyms	Lissamine Rhodamine B PEG4 Acid Chloride; Sulforhodamine B Sulfonamide-PEG4-Acid Chloride; Rhodamine B Sulfonyl Chloride PEG4 Derivative; Acid Chloride Derivative of Lissamine Rhodamine B Sulfonamide PEG4; SRB Sulfonamide-PEG4-COCl; Reactive Red Fluorescent Dye-PEG4-Acid Chloride; N-(Rhodamine B Sulfonyl)-1,13-diamino-4,7,10-trioxatridecan-13-oic acid chloride
EINECS	Contact for details

Quality Control

Our Lissamine Rhodamine B Sulfonamide-Dpeg4-Acid(Chloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and functional testing for reactivity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Activity	Conjugation efficiency ≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.