Description

4-((Dimethylamino)Methyl)-3-Fluorophenylboronic Acid is a specialized organoboron compound featuring both a boronic acid group and a dimethylaminomethyl substituent on a fluorinated aromatic ring. This unique structure makes it a valuable building block in modern synthetic chemistry, particularly for cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boron-containing partner for constructing biaryl and heterobiaryl scaffolds prevalent in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, due to its functionalized aromatic core.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and sensors.
• Ligand Synthesis: Useful for preparing novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	4-((Dimethylamino)Methyl)-3-Fluorophenylboronic Acid
CAS No.	1334173-89-5
Molecular Formula	C9H13BFNO2
Molecular Weight	197.02 g/mol
Synonyms	[4-(Dimethylaminomethyl)-3-fluorophenyl]boronic acid; 3-Fluoro-4-[(dimethylamino)methyl]benzeneboronic acid; 4-(Dimethylaminomethyl)-3-fluorobenzeneboronic acid; (4-(Dimethylaminomethyl)-3-fluorophenyl)boronic acid; Boronic acid, B-[4-[(dimethylamino)methyl]-3-fluorophenyl]-; 1334173-89-5; 3-Fluoro-4-(dimethylaminomethyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-((Dimethylamino)Methyl)-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.