Description

(2-((Diethylamino)Methyl)-5-Fluorophenyl)Boronic Acid is a specialized organoboron compound featuring a diethylaminomethyl and a fluorine substituent on the aromatic ring, making it a valuable building block for modern synthetic chemistry. Its primary value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This high-purity boronic acid is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the fluorine moiety for enhanced biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and molecular probes for target identification and validation in drug discovery.
• Catalyst Ligand Development: The diethylamino group can be utilized to develop novel ligand systems for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, fluorinated biphenyl or heterobiaryl structures.

Basic Information

Product Name	(2-((Diethylamino)Methyl)-5-Fluorophenyl)Boronic Acid
CAS No.	1334170-68-1
Molecular Formula	C11H17BFNO2
Molecular Weight	225.07 g/mol
Synonyms	[2-[(Diethylamino)methyl]-5-fluorophenyl]boronic acid; 5-Fluoro-2-[(diethylamino)methyl]benzeneboronic acid; 2-(Diethylaminomethyl)-5-fluorobenzeneboronic acid; (2-(Diethylaminomethyl)-5-fluorophenyl)boronic acid; Boronic acid, B-[2-[(diethylamino)methyl]-5-fluorophenyl]-; CAS 1334170-68-1
EINECS	Contact for details

Quality Control

Our (2-((Diethylamino)Methyl)-5-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry place (recommended 2-8°C for long-term stability). Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.