Description

5-Fluoro-2-(Isopropoxymethyl)Phenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that benefit from the stability and reactivity of the boronic acid functional group.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular architecture is required.
• Suzuki-Miyaura Cross-Coupling: Functions as a versatile coupling partner with aryl or vinyl halides to form carbon-carbon bonds, a cornerstone reaction in medicinal and process chemistry.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	5-Fluoro-2-(Isopropoxymethyl)Phenylboronic Acid
CAS No.	1333392-80-5
Molecular Formula	C10H14BFO3
Molecular Weight	212.03 g/mol
Synonyms	[5-Fluoro-2-(isopropoxymethyl)phenyl]boronic acid; 2-(Isopropoxymethyl)-5-fluorophenylboronic acid; 5-Fluoro-2-(isopropoxymethyl)benzeneboronic acid; Boronic acid, B-[5-fluoro-2-[(1-methylethoxy)methyl]phenyl]-; 1333392-80-5; 5-Fluoro-2-(isopropoxymethyl)phenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Isopropoxymethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.