Description

2-(Ethoxymethyl)-5-Fluorophenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Building block for the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel boron-containing ligands and catalysts.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and library synthesis for drug discovery.

Basic Information

Product Name	2-(Ethoxymethyl)-5-Fluorophenylboronic Acid
CAS No.	1333391-62-0
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	5-Fluoro-2-(ethoxymethyl)phenylboronic Acid; [5-Fluoro-2-(ethoxymethyl)phenyl]boronic Acid; 2-(Ethoxymethyl)-5-fluorobenzeneboronic Acid; (5-Fluoro-2-(ethoxymethyl)phenyl)boronic Acid; Boronic acid, B-[5-fluoro-2-(ethoxymethyl)phenyl]-; 1333391-62-0; 2-Ethoxymethyl-5-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(Ethoxymethyl)-5-Fluorophenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.