Description

(2-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-value boronic ester derivative, a critical advanced intermediate in modern synthetic chemistry. Its primary commercial value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity building blocks for drug discovery, active ingredient synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require fluorinated aromatic structures.
• Liquid Crystal & OLED Material Precursor: Serves as a crucial intermediate in the manufacture of fluorinated organic electronic materials for displays and lighting.
• Polymer & Resin Modification: Enables the introduction of boronate and fluorinated phenyl groups into polymer backbones to tailor material properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Diagnostic Reagent Synthesis: Potential use in creating probes and labeling agents for biochemical assays and imaging.

Basic Information

Product Name	(2-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No.	1333264-07-5
Molecular Formula	C13H18BFO3
Molecular Weight	252.09 g/mol
Synonyms	2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol; (3-(Hydroxymethyl)-2-fluorophenyl)boronic acid pinacol ester; 2-Fluoro-3-(hydroxymethyl)phenylboronic acid pinacol ester; 2-Fluoro-3-(pinacolatoboryl)benzyl alcohol; 3-(Pinacolatoboraneyl)-2-fluorobenzenemethanol; B-(3-(Hydroxymethyl)-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our (2-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 19F, 11B), and GC/MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. This material is hygroscopic and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.