Description

(5-Fluoro-2-(Pyrrolidin-1-Ylmethyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its unique molecular architecture, which combines a boronic acid functional group with a fluorinated aromatic ring and a pyrrolidine moiety, enabling precise cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing new active ingredients, particularly for constructing complex molecules via Suzuki-Miyaura coupling.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boron reagent for forming carbon-carbon bonds between aromatic rings, a fundamental step in creating complex molecular scaffolds.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the introduction of specific fluorinated aromatic systems is required.
• Material Science: Potential building block for creating organic electronic materials and advanced polymers with tailored properties.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and inhibitors for studying enzyme function and protein interactions.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery programs.

Basic Information

Product Name	(5-Fluoro-2-(Pyrrolidin-1-Ylmethyl)Phenyl)Boronic Acid
CAS No.	1333121-77-9
Molecular Formula	C11H15BFNO2
Molecular Weight	223.06 g/mol
Synonyms	[5-Fluoro-2-(1-Pyrrolidinylmethyl)phenyl]boronic Acid; (5-Fluoro-2-(Pyrrolidin-1-Ylmethyl)phenyl)boronic Acid; 2-(Pyrrolidin-1-ylmethyl)-5-fluorophenylboronic Acid; 5-Fluoro-2-(pyrrolidin-1-ylmethyl)benzeneboronic Acid; B-[5-Fluoro-2-(1-pyrrolidinylmethyl)phenyl]boronic Acid; 1333121-77-9; Boronic acid, B-[5-fluoro-2-(1-pyrrolidinylmethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our (5-Fluoro-2-(Pyrrolidin-1-Ylmethyl)Phenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure to air is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.