Description

tert-Butyl n-[1-(4-Methoxyphenyl)Cyclobutyl]Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclobutyl carbamate structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process chemistry optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Process Chemistry Research: Used in route scouting and optimization studies for the scalable production of complex organic molecules.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Employed in the contract manufacturing of bespoke organic compounds for clinical trial material (CTM) preparation.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	tert-Butyl n-[1-(4-Methoxyphenyl)Cyclobutyl]Carbamate
CAS No.	1332765-86-2
Molecular Formula	C₁₆H₂₃NO₃
Molecular Weight	277.36 g/mol
Synonyms	1-(4-Methoxyphenyl)cyclobutylcarbamic acid tert-butyl ester; tert-Butyl [1-(4-methoxyphenyl)cyclobutyl]carbamate; N-Boc-1-(4-methoxyphenyl)cyclobutanamine; Boc-1-(4-Methoxyphenyl)cyclobutanamine; 1-(4-Methoxyphenyl)cyclobutanamine, N-Boc-; BOC-Protected 1-(4-Methoxyphenyl)cyclobutanamine; tert-Butyl (1-(4-methoxyphenyl)cyclobutyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[1-(4-Methoxyphenyl)Cyclobutyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support customer audits and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.