Description

(5-Fluoro-2-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid is a sophisticated boronic acid derivative featuring a fluorinated phenyl core and a 4-methylpiperidine moiety, making it a valuable building block in modern synthetic chemistry. This compound is essential for facilitating the formation of carbon-carbon bonds via the Suzuki-Miyaura cross-coupling reaction, a cornerstone methodology for constructing complex molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, due to its piperidine scaffold.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides, leveraging the Suzuki coupling to introduce complex aromatic systems.
• Material Science Research: Used in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs, where precise molecular architecture is critical.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the development of molecular probes and sensors via boronic acid-diol interactions.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Item	Details
Product Name	(5-Fluoro-2-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid
CAS No.	1332505-87-9
Molecular Formula	C13H19BFNO2
Molecular Weight	251.11 g/mol
Synonyms	5-Fluoro-2-((4-methyl-1-piperidinyl)methyl)benzeneboronic acid; (5-Fluoro-2-((4-methylpiperidin-1-yl)methyl)phenyl)boronic acid; 2-((4-Methylpiperidin-1-yl)methyl)-5-fluorophenylboronic acid; Boronic acid, B-[5-fluoro-2-[(4-methyl-1-piperidinyl)methyl]phenyl]-; 1332505-87-9; 5-Fluoro-2-((4-methylpiperidin-1-yl)methyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of (5-Fluoro-2-((4-Methylpiperidin-1-Yl)Methyl)Phenyl)Boronic Acid undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and process chemistry. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.