Description

δ2-Cefotetan is a key intermediate in the synthesis of Cefotetan, a second-generation broad-spectrum cephalosporin antibiotic. This compound is critical for ensuring the purity and efficacy of the final active pharmaceutical ingredient (API). It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of advanced antibiotic formulations.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of the antibiotic Cefotetan disodium.
• API Manufacturing: Serves as a high-purity precursor in the commercial-scale production of Cefotetan active pharmaceutical ingredient (API).
• Research & Development: Used in pharmaceutical R&D for developing new cephalosporin derivatives or optimizing synthetic pathways.
• Quality Control Reference: Employed as an analytical reference standard in HPLC and other chromatographic methods for quality assurance.
• Process Chemistry: Integral to process development and scale-up activities within fine chemical and contract manufacturing organizations (CMOs).

Basic Information

Product Name	δ2-Cefotetan
CAS No.	1332499-75-8
Molecular Formula	C17H17N7O8S4
Molecular Weight	575.62 g/mol
Synonyms	(6R,7S)-7-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; δ-2-Cefotetan; Cefotetan δ-2 Isomer; Cefotetan Intermediate; 7-Methoxy-δ2-Cefotetan; (6R,7S)-7-Methoxy-7-[(2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino)acetamido]-3-[(1-methyl-1H-tetrazol-5-ylthio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our δ2-Cefotetan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.