Description

Acepromazine-D6 Maleate is a deuterated analog of the phenothiazine derivative acepromazine, specifically labeled with six deuterium atoms. This high-purity stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reliability in analytical results. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and forensic toxicology labs engaged in method development, pharmacokinetic studies, and drug metabolism research for the parent compound.

Application

• Primary use as an Internal Standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of acepromazine.
• Critical component in Pharmacokinetic and Bioavailability Studies to track drug absorption, distribution, metabolism, and excretion (ADME).
• Essential for Forensic and Clinical Toxicology analysis, providing definitive identification and measurement of acepromazine in biological matrices.
• Used in Veterinary Pharmaceutical Research for developing and validating analytical methods for sedative and tranquilizer formulations.
• Supporting Drug Metabolism and Metabolite Identification studies to understand biotransformation pathways.
• Application in Quality Control and Stability Testing of pharmaceutical products containing acepromazine.

Basic Information

Product Name	Acepromazine-D6 Maleate
CAS No.	1331655-50-5
Molecular Formula	C19H16D6N2OS • C4H4O4
Molecular Weight	428.51 g/mol
Synonyms	2-Acetyl-10-(3-dimethylaminopropyl)phenothiazine-D6 Maleate; Acepromazine-d6 Maleate Salt; Deuterated Acepromazine Maleate; [2H6]-Acepromazine Maleate; Acepromazine (dimethyl-d6) Maleate; Notensyl-d6 Maleate; Atravet-d6 Maleate; Acetylpromazine-d6 Maleate
EINECS	Contact for details

Quality Control

Our Acepromazine-D6 Maleate is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (≥98 atom % D), chemical purity (by HPLC), and confirmation of structure. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable and reproducible performance in your LC-MS/MS and GC-MS methods.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.