Description

Carphenazine-D4 Dimaleate is a high-purity, deuterium-labeled internal standard critical for modern analytical quantification. This stable isotope-labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based methods by correcting for analyte loss during sample preparation and instrument variability. It is primarily required by pharmaceutical research and development laboratories, contract research organizations (CROs), and forensic toxicology facilities engaged in precise pharmacokinetic studies, metabolic profiling, and bioanalytical method validation.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of Carphenazine and its metabolites in biological matrices (plasma, serum, urine).
• Use in pharmacokinetic (PK) and pharmacodynamic (PD) studies to determine drug absorption, distribution, metabolism, and excretion.
• Critical component in the development and validation of GLP/GCP-compliant bioanalytical methods for clinical trials.
• Application in forensic and clinical toxicology for the accurate identification and quantification of substances.
• Use in drug metabolism and disposition (DMPK) research to track and quantify metabolic pathways.
• Supporting quality control and stability testing in pharmaceutical manufacturing where precise measurement is required.

Basic Information

Product Name	Carphenazine-D4 Dimaleate
CAS No.	1331636-24-8
Molecular Formula	C29H30D4N4O8
Molecular Weight	Contact for details
Synonyms	Carphenazine-d4; Carphenazine (phenyl-d4) Dimaleate; 10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]-2-(trideuteriophenyl)phenothiazine Dimaleate; 2-(2,3,4,5,6-Pentadeuteriophenyl)-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine Dimaleate; Deuterated Carphenazine Dimaleate; Internal Standard for Carphenazine
EINECS	Contact for details

Quality Control

Our Carphenazine-D4 Dimaleate is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, assay, isotopic enrichment, and purity by HPLC. We adhere to relevant industry standards for reference materials, and our quality commitment ensures reliable and reproducible performance in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥98.0 atom % D
Chemical Purity (HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.