Description

(1S)-N-((3S)-1-Azabicyclo[2.2.2]oct-3-yl)-1,2,3,4-tetrahydro-1-naphthalenecarboxamide-D1 is a deuterated derivative of a complex chiral amine, designed for advanced research and development applications. This compound is valued for its role as a stable isotope-labeled standard, providing critical utility in analytical and metabolic studies. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for drug discovery, pharmacokinetics, and environmental fate analysis.

Application

• Internal Standard for Mass Spectrometry: Used in quantitative LC-MS/MS analysis for accurate measurement of its non-deuterated counterpart in biological matrices.
• Metabolic Pathway Tracing: Employed in drug metabolism and pharmacokinetics (DMPK) studies to track and identify metabolites.
• Pharmaceutical Reference Standard: Serves as a certified reference material for quality control and method validation in API development.
• Isotope Dilution Analysis: Critical for achieving high precision and accuracy in environmental and residue analysis.
• Mechanistic Studies: Aids in reaction mechanism elucidation and stereochemical investigations in synthetic chemistry.
• Precursor for Labeled Compounds: Acts as a building block for the synthesis of more complex deuterated molecules.

Basic Information

Product Name	(1S)-N-((3S)-1-Azabicyclo[2.2.2]oct-3-yl)-1,2,3,4-tetrahydro-1-naphthalenecarboxamide-D1
CAS No.	1330266-39-1
Molecular Formula	C18H24D1N2O
Molecular Weight	284.41 g/mol (approx.)
Synonyms	(1S)-N-((3S)-1-Azabicyclo[2.2.2]octan-3-yl)-1,2,3,4-tetrahydro-1-naphthamide-D1; (S)-N-((S)-quinuclidin-3-yl)-1,2,3,4-tetrahydro-1-naphthamide-D1; Deuterated Quinuclidine-Tetralin Carboxamide; 1,2,3,4-Tetrahydro-1-naphthalenecarboxamide, N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-, (1S)-, deuterated; (1S,3S)-Deuterated Carboxamide Derivative; Isotope-labeled Chiral Amide; [D1]-Labeled Tetrahydro-Naphthamide
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing assay, isotopic enrichment (D-content), chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable for reference standard production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.