Description

Rac Bendroflumethiazide-D5 CAS NO 1330183-13-5 is a deuterated isotopologue of the thiazide diuretic bendroflumethiazide, where five hydrogen atoms are replaced with deuterium. This stable isotope-labeled compound is a critical reference standard and internal standard for ensuring analytical accuracy and reliability in quantitative mass spectrometry. It is essential for researchers and quality control laboratories in the pharmaceutical and analytical chemistry sectors who require precise measurement of bendroflumethiazide in complex matrices such as biological fluids, environmental samples, and pharmaceutical formulations.

Application

• Primary use as a stable isotope-labeled internal standard for the accurate quantification of bendroflumethiazide via LC-MS/MS and GC-MS methods.
• Critical component in pharmacokinetic and bioequivalence studies to track drug metabolism and absorption in clinical research.
• Reference material for method development and validation in regulatory-compliant analytical laboratories.
• Quality control applications in pharmaceutical manufacturing to assay active pharmaceutical ingredient (API) purity and content.
• Use in forensic and anti-doping analysis for the definitive identification and measurement of the diuretic.
• Tool for environmental monitoring studies investigating the fate and persistence of pharmaceutical pollutants.
• Research chemical for metabolic pathway elucidation and deuterium isotope effect studies in medicinal chemistry.

Basic Information

Product Name	Rac Bendroflumethiazide-D5
CAS No.	1330183-13-5
Molecular Formula	C15H9D5F3N3O4S2
Molecular Weight	429.43 g/mol (approximate)
Synonyms	Bendroflumethiazide-d5; Bendrofluazide-d5; 3-Benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide-d5; Bendroflumethiazide (phenyl-d5); Naturetin-d5; Aprinox-d5; Benzylhydroflumethiazide-d5; 7-Sulfamoyl-3,4-dihydro-6-(trifluoromethyl)-3-(phenyl-d5-methyl)-1,2,4-benzothiadiazine 1,1-dioxide
EINECS	Contact for details

Quality Control

Every batch of Rac Bendroflumethiazide-D5 is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to support its use in regulated environments, including certificates of analysis (COA) detailing isotopic purity, chemical purity, and solvent content. Our quality commitment ensures the material meets the high standards required for pharmaceutical research and analytical reference applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (chemical purity)
Isotopic Purity (MS)	≥98.0 atom % D
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.