Description

Ramifenazon-D6 is a deuterium-labeled analog of the pharmaceutical compound Ramifenazon, specifically designed for use as an internal standard in quantitative analytical methods. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of mass spectrometry-based analyses, particularly in pharmacokinetic and metabolism studies. It is a critical tool for researchers and quality control laboratories in the pharmaceutical and biotechnology sectors who require precise measurement of the parent compound in complex biological matrices.

Application

• Internal Standard for LC-MS/MS: Serves as a primary internal standard for the precise quantification of Ramifenazon in bioanalytical methods using Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS).
• Drug Metabolism and Pharmacokinetics (DMPK): Used in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to track and quantify the parent drug and its metabolites.
• Pharmaceutical Quality Control: Employed in the development and validation of analytical methods for the assay and impurity profiling of Ramifenazon in active pharmaceutical ingredients (APIs) and finished drug products.
• Clinical Research: Facilitates accurate drug concentration monitoring in plasma, serum, and other biological samples during clinical trials.
• Forensic and Toxicological Analysis: Aids in the specific and sensitive detection of Ramifenazon in forensic investigations or cases of suspected overdose.

Basic Information

Product Name	Ramifenazon-D6
CAS No.	1330180-51-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ramifenazon-d6; Deuterated Ramifenazon; Ramifenazon (hexadeuterated); 4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N,N,2-trimethyl-5-(trideuteriomethyl)(2H3)pyrazol-3-amine; Ramifenazon Internal Standard
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high isotopic purity and chemical stability, which are critical for their performance as analytical standards. Each batch is characterized using advanced spectroscopic and chromatographic techniques. Certificates of Analysis (COA) detailing isotopic enrichment (D%), chemical purity, and analytical data are provided to support your method validation and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider keeping the product in a freezer (-20°C) to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Isotopic Purity (D%)	≥ 98% (by MS)
Chemical Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.