Description

6-Amino-2-Thiouracil-13C2 is a stable isotope-labeled analog of 6-amino-2-thiouracil, where two carbon atoms are replaced with the carbon-13 isotope. This compound is essential for advanced analytical and research applications where precise molecular tracking and quantification are required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for use as an internal standard in mass spectrometry, metabolic pathway studies, and the development of labeled active pharmaceutical ingredients (APIs).

Application

• Internal Standard for LC-MS/MS: Provides high-accuracy quantification in bioanalytical methods for pharmacokinetic and metabolomic studies.
• Metabolic Pathway Tracing: Enables the detailed investigation of drug metabolism and biochemical pathways in research.
• Synthesis of Isotope-Labeled APIs: Serves as a key building block for the preparation of carbon-13 labeled pharmaceutical compounds.
• Proteomics and Biomarker Research: Used in quantitative proteomics to improve the precision of protein and peptide analysis.
• Environmental Fate Studies: Assists in tracing the degradation and transformation of chemical compounds in environmental samples.
• Quality Control Reference Material: Acts as a certified reference standard to ensure analytical method validity and regulatory compliance.

Basic Information

Product Name	6-Amino-2-Thiouracil-13C2
CAS No.	1330170-14-3
Molecular Formula	C413C2H6N4OS
Molecular Weight	~160.15 g/mol (for 13C2 labeled form)
Synonyms	6-Amino-2-mercapto-4-pyrimidinol-13C2; 2-Thio-6-aminouracil-13C2; 6-Amino-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one-13C2; 6-Amino-2-thio-4-pyrimidinol-13C2; 2,6-Diamino-4(3H)-pyrimidinethione-13C2; 13C2-labeled 6-Amino-2-thiouracil; ATA-13C2; Isotopically labeled 6-ATU
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Thiouracil-13C2 is manufactured under strict quality systems to ensure high isotopic and chemical purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and impurity profiles. We adhere to relevant industry standards for reference materials, and custom synthesis and purification to meet specific client requirements are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.