Description

2-Amino-6-[(4-Fluorobenzyl)-Amino]-3-Nitropyridine-D4 is a deuterated pyridine derivative, a high-value stable isotope-labeled compound essential for advanced analytical and research applications. Its core value lies in its use as an internal standard in mass spectrometry, enabling precise quantification and reliable data in complex matrices. This compound is primarily needed by pharmaceutical R&D teams, contract research organizations (CROs), and analytical laboratories engaged in drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and forensic analysis.

Application

• Primary use as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and High-Resolution Mass Spectrometry (HRMS).
• Critical for quantitative bioanalysis in drug discovery and development, ensuring accuracy in measuring parent drugs or metabolites in biological fluids.
• Supporting metabolite identification and profiling studies to understand drug biotransformation pathways.
• Enabling pharmacokinetic (PK) and toxicokinetic (TK) studies with high precision and minimal interference from endogenous compounds.
• Application in forensic and anti-doping analysis for the definitive identification and quantification of specific analytes.
• Use in academic and industrial research involving the mechanism of action of related pyridine-based compounds.

Basic Information

Item	Detail
Product Name	2-Amino-6-[(4-Fluorobenzyl)-Amino]-3-Nitropyridine-D4
CAS No.	1330170-09-6
Molecular Formula	C12H8D4FN4O2
Molecular Weight	263.27 g/mol (deuterated form)
Synonyms	2-Amino-6-[(4-fluorobenzyl)amino]-3-nitropyridine-d4; 2-Amino-6-((4-fluorobenzyl)amino)-3-nitropyridine-d4; 3-Nitro-2-amino-6-[(4-fluorobenzyl)amino]pyridine-d4; 2,6-Diamino-3-nitropyridine-d4 derivative; Deuterated 2-Amino-6-[(4-Fluorobenzyl)-Amino]-3-Nitropyridine; Stable Isotope Labeled Pyridine Derivative; Internal Standard for LC-MS (1330170-09-6)
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-[(4-Fluorobenzyl)-Amino]-3-Nitropyridine-D4 is manufactured and controlled under a strict quality management system. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR (¹H, ²H, ¹³C) for structural and isotopic confirmation and HPLC for chemical purity assessment. Certificates of Analysis (COA) detailing batch-specific results for purity, isotopic enrichment, and identity are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (²H NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.