Description

4-[4-[(5S)-5-(Aminomethyl)-2-Oxo-3-Oxazolidinyl]Phenyl]-3-Morpholinone-D4 is a deuterated isotopologue of a key pharmaceutical intermediate, offering enhanced stability and utility in advanced research and development. This compound is critical for applications requiring precise metabolic and pharmacokinetic studies, particularly in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on deuterium-labeled compounds and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of deuterated active pharmaceutical ingredients (APIs).
• Metabolic Studies: Used as an internal standard or tracer in mass spectrometry for drug metabolism and pharmacokinetics (DMPK) research.
• Isotope Labeling: Serves as a precursor for the preparation of deuterium-labeled compounds to study reaction mechanisms and pathways.
• Analytical Reference Standard: Provides a high-purity standard for quality control and method validation in analytical laboratories.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new drug candidates, particularly within the oxazolidinone and morpholinone chemical classes.
• Process Chemistry: Used in the development and scale-up of synthetic routes for complex molecules.

Basic Information

Product Name	4-[4-[(5S)-5-(Aminomethyl)-2-Oxo-3-Oxazolidinyl]Phenyl]-3-Morpholinone-D4
CAS No.	1330169-92-0
Molecular Formula	C₁₄H₁₃D₄N₃O₄
Molecular Weight	291.31 g/mol (approx.)
Synonyms	3-Morpholinone, 4-[4-[(5S)-5-(aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-, D4; Deuterated Linezolid Intermediate; (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one-d4; 4-[4-[(5S)-5-(Aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]-1,4-oxazin-3-one-d4; Linezolid-d4 Related Compound; (5S)-3-[4-(3-Oxo-4-morpholinyl)phenyl]-5-(aminomethyl)-2-oxazolidinone-d4; Deuterated PNU-100766 Derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and development needs. Certificates of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles are available upon request. Our quality systems are designed to meet the stringent requirements of pharmaceutical and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.