Description

Bis(2-Chloroethyl)Methylamine-D4 Hydrochloride is a high-purity, deuterium-labeled analog of a nitrogen mustard compound, specifically designed for advanced research and analytical applications. This stable isotope-labeled standard is critical for ensuring accuracy and reliability in quantitative mass spectrometry and metabolic studies. It is primarily utilized by pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) engaged in drug development, pharmacokinetics, and forensic analysis.

Application

• Internal Standard for LC-MS/MS: Serves as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the analysis of its non-deuterated counterpart.
• Metabolic Pathway Tracing: Used in deuterium labeling studies to investigate the metabolic fate, distribution, and biotransformation of nitrogen mustard compounds.
• Pharmaceutical R&D: Essential for method development and validation in the research of alkylating agents and related therapeutic compounds.
• Forensic and Toxicological Analysis: Enables precise detection and quantification in complex biological matrices for clinical and forensic investigations.
• Quality Control and Reference Material: Acts as a certified reference material (CRM) for calibrating analytical instruments and ensuring data integrity in GLP/GMP environments.

Basic Information

Product Name	Bis(2-Chloroethyl)Methylamine-D4 Hydrochloride
CAS No.	1329812-14-7
Molecular Formula	C5H7D4Cl2N • HCl
Molecular Weight	Contact for details
Synonyms	Methylbis(2-chloroethyl)amine-D4 Hydrochloride; Nitrogen Mustard-D4 Hydrochloride; HN2-D4 Hydrochloride; Mechlorethamine-D4 Hydrochloride; 2-Chloro-N-(2-chloroethyl)-N-methylethanamine-D4 Hydrochloride; Deuterated Mustargen Hydrochloride; Bis(β-chloroethyl)methylamine-D4 Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Bis(2-Chloroethyl)Methylamine-D4 Hydrochloride is manufactured under strict quality systems and undergoes comprehensive analytical characterization. We guarantee high chemical and isotopic purity to meet the exacting demands of research and regulatory submission support. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting specifications for identity, purity (by HPLC), isotopic enrichment, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.