Description

4-[3-(Dibutylamino)Propoxy]Benzoic Acid-D6 Hydrochloride is a high-purity, deuterium-labeled internal standard critical for ensuring analytical accuracy in quantitative mass spectrometry. This compound is specifically designed for use in pharmacokinetic, metabolic, and bioanalytical studies, providing unmatched precision for trace-level quantification. It is an essential reagent for pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers requiring reliable and consistent reference materials for method development and validation.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS) bioanalysis.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in studies to track the absorption, distribution, metabolism, and excretion (ADME) of the parent, non-deuterated compound.
• Biomarker Quantification: Enables precise measurement of target analytes in complex biological matrices such as plasma, serum, and tissue homogenates.
• Pharmaceutical Quality Control: Supports impurity profiling and assay validation for active pharmaceutical ingredients (APIs) during manufacturing.
• Clinical Research: Facilitates accurate therapeutic drug monitoring (TDM) and clinical trial sample analysis.
• Stable Isotope Labeling: Serves as a key reagent in the synthesis of other deuterated compounds for advanced research applications.

Basic Information

Item	Detail
Product Name	4-[3-(Dibutylamino)Propoxy]Benzoic Acid-D6 Hydrochloride
CAS No.	1329808-49-2
Molecular Formula	C19H27D6ClNO3
Molecular Weight	Contact for details
Synonyms	Benzoic acid-D6, 4-[3-(dibutylamino)propoxy]-, hydrochloride; 4-(3-(Dibutylamino)propoxy)benzoic Acid-d6 HCl; Deuterated 4-[3-(Dibutylamino)propoxy]benzoic acid hydrochloride; 4-(3-(Dibutylamino)propoxy)benzoic-2,3,4,5,6-d5 acid (carboxy-d) hydrochloride; DBAPBA-d6 HCl; Internal Standard for DBAPBA.
EINECS	Contact for details

Quality Control

Every batch of 4-[3-(Dibutylamino)Propoxy]Benzoic Acid-D6 Hydrochloride is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes to ensure it meets the stringent requirements for use as an analytical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.