Description

Diazoxide-15N,13C2 is a stable isotope-labeled analog of the antihypertensive and hyperglycemic agent Diazoxide, specifically enriched with carbon-13 and nitrogen-15. This compound is an essential internal standard for quantitative mass spectrometry, enabling precise and accurate pharmacokinetic and metabolic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in advanced bioanalytical method development and drug metabolism research.

Application

• As a stable isotope-labeled internal standard for the quantification of Diazoxide in biological matrices (e.g., plasma, serum, urine) using LC-MS/MS.
• For conducting high-precision pharmacokinetic (PK) and bioavailability studies in drug development.
• In metabolite identification and profiling studies to trace metabolic pathways.
• Use in clinical research to monitor drug levels and ensure accurate therapeutic drug monitoring (TDM).
• For method validation according to regulatory guidelines (e.g., FDA, EMA) to ensure assay specificity and accuracy.
• Application in forensic and anti-doping analysis for the definitive identification of Diazoxide.

Basic Information

Product Name	Diazoxide-15N,13C2
CAS No.	1329613-88-8
Molecular Formula	C813C2H7ClN215NO2S
Molecular Weight	233.66 (for 13C2, 15N)
Synonyms	7-Chloro-3-methyl-13C2-2H-1,2,4-benzothiadiazine 1,1-dioxide-15N; Diazoxide (13C2, 15N); Diazoxide-13C2,15N; 7-Chloro-3-methyl-13C2-1,2,4-benzothiadiazine-15N 1,1-dioxide; Diazoxide (methyl-13C2, 15N); Stable Isotope Labeled Diazoxide; Diazoxide Internal Standard; Hyperstat-13C2,15N
EINECS	Contact for details

Quality Control

Every batch of Diazoxide-15N,13C2 is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity for critical analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request and provide detailed data on isotopic enrichment, chemical purity, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98% (chemical purity)
Isotopic Enrichment	≥99 atom % 13C; ≥99 atom % 15N
Isotopic Purity (MS)	≥98%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.