Description

Theophyllidine-D6 Hydrochloride is a high-purity, deuterium-labeled internal standard critical for accurate quantitative analysis in advanced research. This stable isotope-labeled compound is essential for ensuring precision and reliability in mass spectrometry-based assays, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers specializing in drug development and bioanalytical method validation.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and LC-MS/MS for the quantification of Theophyllidine and related xanthine derivatives.
• Critical component in bioanalytical method development and validation for clinical and preclinical studies.
• Enables precise pharmacokinetic (PK) and metabolism studies by correcting for matrix effects and instrument variability.
• Supports doping control analysis in sports medicine for detecting stimulants.
• Used in forensic toxicology for the accurate identification and quantification of substances.
• Facilitates drug discovery research involving adenosine receptor antagonists.
• Essential for quality control and stability testing of pharmaceutical formulations containing related actives.

Basic Information

Product Name	Theophyllidine-D6 Hydrochloride
CAS No.	1329613-52-6
Molecular Formula	C7H2D6N4O2 • HCl
Molecular Weight	230.68 g/mol (approx.)
Synonyms	1,3-Dimethyl-7H-purine-2,6-dione-d6 hydrochloride; 1,3-Dimethylxanthine-d6 hydrochloride; Theophylline-d6 hydrochloride; 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione-d6 hydrochloride; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, hydrochloride-d6; 1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purine-d6 hydrochloride; Deuterated Theophylline Hydrochloride
EINECS	Contact for details

Quality Control

Our Theophyllidine-D6 Hydrochloride is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment, chemical purity, and residual solvent content. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable performance as an internal standard. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.