Description

Chlorpromazine-13C,D3 Hydrochloride is a stable isotope-labeled analog of the classic antipsychotic drug, chlorpromazine. This compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in bioanalytical research and pharmaceutical development. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, contract research organization (CRO), and forensic toxicology sectors who require precise quantification of chlorpromazine and its metabolites in complex biological matrices.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for pharmacokinetic and bioequivalence studies.
• Drug Metabolism and Pharmacokinetics (DMPK): Used to trace and quantify the metabolic pathways and clearance rates of chlorpromazine in vivo.
• Forensic and Clinical Toxicology: Enables accurate measurement of chlorpromazine levels in blood, plasma, or urine for diagnostic and legal purposes.
• Pharmaceutical Quality Control: Supports assay validation and impurity profiling in the manufacturing process of chlorpromazine-based medications.
• Biomedical Research: Facilitates precise research on the drug's mechanism of action, distribution, and stability in biological systems.

Basic Information

Product Name	Chlorpromazine-13C,D3 Hydrochloride
CAS No.	1329612-87-4
Molecular Formula	C17[13C]H16D3ClN2S • HCl
Molecular Weight	~ 359.78 g/mol
Synonyms	2-Chloro-10-[3-(dimethylamino)propyl]-13C,D3-phenothiazine Hydrochloride; Chlorpromazine-(phenyl-13C, N,N-dimethyl-d3) Hydrochloride; 3-(2-Chloro-10H-13C,D3-phenothiazin-10-yl)-N,N-dimethyl-d3-propan-1-amine Hydrochloride; Chlorpromazine-d3 (phenyl-13C) Hydrochloride; Largactil-13C,D3 Hydrochloride; Thorazine-13C,D3 Hydrochloride; CPZ-13C,D3 HCl
EINECS	Contact for details

Quality Control

Our Chlorpromazine-13C,D3 Hydrochloride is manufactured under strict quality systems to ensure exceptional isotopic purity and chemical integrity, meeting the rigorous demands of analytical reference standards. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (e.g., 13C, D), chemical purity by HPLC, and confirmation of structure by NMR and MS. We adhere to relevant industry guidelines for stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. The product is light-sensitive (store away from light). Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.