Description

4'-Methyl-D3 Aminorex CAS NO 1329610-51-6 is a deuterated analog of the aminorex class, specifically labeled with three deuterium atoms at the 4'-methyl position. This stable isotope-labeled compound is a critical reference standard and internal standard for precise analytical quantification in research and development. It is primarily utilized by pharmaceutical researchers, forensic toxicologists, and analytical chemists working in metabolism studies, pharmacokinetic profiling, and method validation. The deuterium labeling provides a distinct mass signature essential for advanced mass spectrometry techniques.

Application

• Analytical Reference Standard: Serves as a certified standard for the calibration and validation of analytical methods, including LC-MS/MS and GC-MS, for the detection of aminorex derivatives.
• Metabolite Identification & Pharmacokinetics: Used as a stable isotope internal standard to accurately quantify parent drug and metabolites in biological matrices during ADME (Absorption, Distribution, Metabolism, Excretion) studies.
• Forensic Analysis & Toxicology: Essential for confirmatory testing and quantitative analysis in forensic laboratories to distinguish and measure specific substances with high legal defensibility.
• Drug Development Research: Supports preclinical and clinical research by enabling precise measurement of drug concentrations, aiding in dose-response studies and safety assessments.
• Isotope Dilution Mass Spectrometry (IDMS): The deuterium label is ideal for IDMS, a gold-standard technique for achieving high accuracy and minimizing matrix effects in complex samples.
• Quality Control & Method Development: Employed in pharmaceutical QC laboratories to develop, optimize, and ensure the robustness of analytical procedures for impurity profiling and assay determination.

Basic Information

Product Name	4'-Methyl-D3 Aminorex
CAS No.	1329610-51-6
Molecular Formula	C11H10D3N2O
Molecular Weight	192.25 g/mol
Synonyms	4'-Methylaminorex-d3; 4-Methylaminorex-d3; 4,5-Dihydro-4-methyl-5-phenyl-2-oxazolamine-d3; 4-Methyl-5-phenyl-2-amino-2-oxazoline-d3; 4'-Methyl-2-amino-5-phenyl-2-oxazoline-d3; 4-MAR-d3; Deuterated 4-Methylaminorex; 4'-Methyl-D3-2-Amino-5-phenyl-2-oxazoline
EINECS	Contact for details

Quality Control

Every batch of 4'-Methyl-D3 Aminorex is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail purity, isotopic enrichment, and impurity profiles, ensuring traceability and compliance with research-grade standards. Our quality protocols are designed to meet the exacting requirements of analytical and forensic laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.