Description

Synephrine-13C2,15N Hydrochloride Salt is a high-purity, stable isotope-labeled internal standard essential for advanced analytical research. This compound is critical for ensuring the accuracy and reliability of quantitative mass spectrometry analyses in complex biological matrices. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and forensic toxicology labs for method development, validation, and precise pharmacokinetic studies.

Application

• Quantitative Bioanalysis: Used as an internal standard in LC-MS/MS and GC-MS methods for the accurate quantification of synephrine and related alkaloids in plasma, serum, and urine.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) for dietary supplements and pharmaceutical formulations containing synephrine.
• Metabolomics Research: Facilitates the identification and quantification of metabolic pathways and biomarkers in nutritional and clinical studies.
• Forensic and Doping Control Analysis: Provides definitive reference material for the detection and confirmation of synephrine in forensic toxicology and anti-doping programs.
• Method Development and Validation: Serves as a critical tool for developing, optimizing, and validating robust analytical methods in compliance with FDA, EMA, and ICH guidelines.
• Quality Control in Manufacturing: Supports impurity profiling and assay verification in the production of synephrine-based products.

Basic Information

Product Name	Synephrine-13C2,15N Hydrochloride Salt
CAS No.	1329499-30-0
Molecular Formula	C913C2H1415NO2•HCl
Molecular Weight	Contact for details
Synonyms	p-Synephrine-13C2,15N hydrochloride; (±)-Synephrine-13C2,15N hydrochloride; Oxedrine-13C2,15N hydrochloride; 4-[1-Hydroxy-2-(methylamino)ethyl]phenol-13C2,15N hydrochloride; m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol-13C2,15N hydrochloride; Racemic Synephrine-13C2,15N HCl; Isotopically Labeled Synephrine HCl
EINECS	Contact for details

Quality Control

Every batch of Synephrine-13C2,15N Hydrochloride Salt is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We guarantee high chemical and isotopic purity verified by NMR (1H, 13C), mass spectrometry, and HPLC. Certificates of Analysis (COA) detailing isotopic enrichment, purity, and all relevant specifications are provided to ensure traceability and compliance with your research or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98% (chemical purity)
Isotopic Enrichment	≥99 atom % 13C; ≥99 atom % 15N
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.