Description

3-Bromo-5-Fluoro-n-Propylbenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated benzamide structure. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, including kinase inhibitors and other small molecule drugs. The precise molecular architecture offers a critical handle for further functionalization in complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop compounds with improved efficacy and selectivity.
• Chemical Synthesis: Serves as a precursor for further functionalization, enabling the creation of more complex molecules through cross-coupling and amidation reactions.
• Agrochemical Development: Potential application as an intermediate in the synthesis of advanced crop protection agents and herbicides.
• Material Science: Can be utilized in the development of specialty polymers and liquid crystals due to its aromatic and halogenated properties.

Basic Information

Product Name	3-Bromo-5-Fluoro-n-Propylbenzamide
CAS No.	1329280-50-3
Molecular Formula	C10H11BrFNO
Molecular Weight	260.10 g/mol
Synonyms	3-Bromo-5-fluoropropylbenzamide; N-Propyl-3-bromo-5-fluorobenzamide; Benzamide, 3-bromo-5-fluoro-N-propyl-; 1329280-50-3; 3-Bromo-5-fluoro-N-propylbenzamide
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-n-Propylbenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, confirming compliance with customer specifications and relevant industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.