Description

tert-Butyldicyclohexylphosphine Tetrafluoroborate is a high-purity, air-stable phosphonium salt widely used as a precursor to a highly active and sterically demanding tertiary phosphine ligand. This compound is valued for its role in facilitating challenging cross-coupling and other transition metal-catalyzed reactions, offering improved catalyst performance and selectivity. It is an essential reagent for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality ligands for catalyst development and scale-up.

Application

• Precursor for Buchwald-type Phosphine Ligands: In-situ generation of tert-butyldicyclohexylphosphine (tBuCy2P), a key ligand in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling).
• Pharmaceutical Intermediate Synthesis: Enabling the construction of complex carbon-nitrogen and carbon-carbon bonds in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel herbicide and insecticide candidates through efficient catalytic cycles.
• Polymer & Materials Science: Catalyst component for the synthesis of specialty polymers and functional organic materials.
• Homogeneous Catalysis Development: A valuable tool for exploring new catalytic methodologies in academic and industrial R&D laboratories.
• Ligand Screening Libraries: Supplied as a standardized component for high-throughput screening of catalyst systems.

Basic Information

Product Name	tert-Butyldicyclohexylphosphine Tetrafluoroborate
CAS No.	1327162-47-9
Molecular Formula	C16H31BF4P
Molecular Weight	332.20 g/mol
Synonyms	t-Butyldicyclohexylphosphonium Tetrafluoroborate; tert-Butyl(dicyclohexyl)phosphonium Tetrafluoroborate; tBuCy2PH+ BF4-; Phosphonium, tert-butyldicyclohexyl-, tetrafluoroborate(1-); Precursor to tBuCy2P; Air-stable phosphine precursor; Dicyclohexyl(tert-butyl)phosphonium tetrafluoroborate
EINECS	Contact for details

Quality Control

Our tert-Butyldicyclohexylphosphine Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and HPLC, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) with full traceability are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use to maintain optimal quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.