Description

Bis(2-(Di-tert-Butylphosphino)Ethyl)Amine Hydrochloride is a high-value, specialized organophosphorus ligand used in homogeneous catalysis. This compound is critical for enabling highly selective and efficient cross-coupling reactions in fine chemical and pharmaceutical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel synthetic pathways.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig amination, and C-N bond formation.
• For the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs) requiring high selectivity.
• In the development of advanced catalytic systems for the production of agrochemicals and specialty chemicals.
• As a key component in catalyst screening kits for high-throughput experimentation in process chemistry.
• For academic and industrial research in organometallic chemistry and new catalytic methodologies.

Basic Information

Product Name	Bis(2-(Di-tert-Butylphosphino)Ethyl)Amine Hydrochloride
CAS No.	1326805-03-1
Molecular Formula	C18H42ClNP2
Molecular Weight	369.92 g/mol
Synonyms	Bis[2-(Di-tert-butylphosphino)ethyl]amine Hydrochloride; dtbpeamine HCl; N,N-Bis[2-(di-tert-butylphosphino)ethyl]amine Hydrochloride; 1,2-Ethanediamine, N1,N2-bis[2-(di-tert-butylphosphino)ethyl]-, hydrochloride; PNP Pincer Ligand Precursor; (tBuPNP)HCl; dtbpe·HCl
EINECS	Contact for details

Quality Control

Our Bis(2-(Di-tert-Butylphosphino)Ethyl)Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for catalytic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (NMR)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.