Description

Benzonitrile, 3-Bromo-2-Fluoro-5-Nitro- CAS NO 1326714-50-4 is a high-purity, multi-functional aromatic nitrile derivative, distinguished by its unique halogen and nitro substitution pattern. This compound is a critical advanced pharmaceutical intermediate and versatile building block for complex organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to construct novel active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Acts as a scaffold for creating fluorescent tags and molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Benzonitrile, 3-Bromo-2-Fluoro-5-Nitro-
CAS No.	1326714-50-4
Molecular Formula	C7H2BrFN2O2
Molecular Weight	244.99 g/mol
Synonyms	3-Bromo-2-fluoro-5-nitrobenzonitrile; 2-Fluoro-3-bromo-5-cyanobenzene; 2-Fluoro-3-bromo-5-nitrobenzonitrile; 5-Nitro-3-bromo-2-fluorobenzonitrile; Benzonitrile, 3-bromo-2-fluoro-5-nitro-; 3-Bromo-2-fluoro-5-nitro-benzonitrile; 2-Fluoro-3-bromo-5-nitrobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Fluoro-5-Nitrobenzonitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with high-purity standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.