Description

4-Bromo-2-Fluorophenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the halogenated fluorophenyl moiety is a valuable structural component.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and as a building block for functional materials.
• Organic Electronics: Serves as a monomer or intermediate in the synthesis of conjugated polymers and small molecules for OLED and semiconductor applications.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	4-Bromo-2-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1326316-85-1
Molecular Formula	C₁₂H₁₅BBrFO₂
Molecular Weight	301.96 g/mol
Synonyms	4-Bromo-2-fluorobenzeneboronic acid pinacol ester; 2-Fluoro-4-bromophenylboronic acid pinacol ester; (4-Bromo-2-fluorophenyl)boronic acid pinacol ester; 4-Bromo-2-fluorophenyl-Bpin; B-(4-Bromo-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 4-Bromo-2-fluorophenylboronate; 1326316-85-1
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive applications. We provide comprehensive analytical data, including HPLC, NMR, and GC-MS profiles. A Certificate of Analysis (COA) detailing purity, identity, and impurity levels is supplied with every batch to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.