Description

Niflumic Acid-13C6 is a stable isotope-labeled analog of the non-steroidal anti-inflammatory drug (NSAID) niflumic acid, where six carbon atoms are replaced with the carbon-13 isotope. This compound is an essential internal standard for the precise and accurate quantification of niflumic acid in complex biological matrices using advanced analytical techniques like LC-MS/MS. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development.

Application

• Bioanalytical Method Development: Serves as a critical internal standard for developing and validating sensitive LC-MS/MS methods for niflumic acid quantification.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Doping Control and Forensic Analysis: Used as a reference standard in sports anti-doping programs and forensic toxicology to detect and confirm the presence of niflumic acid.
• Pharmaceutical Quality Control: Acts as a certified reference material for assay and impurity profiling of niflumic acid in active pharmaceutical ingredient (API) and finished product analysis.
• Environmental and Food Safety Testing: Facilitates the detection and quantification of niflumic acid residues in environmental water samples or food products of animal origin.

Basic Information

Product Name	Niflumic Acid-13C6
CAS No.	1325559-33-8
Molecular Formula	13C6C7H6F3N2O2
Molecular Weight	~286.2
Synonyms	2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid-13C6; 2-{[3-(Trifluoromethyl)phenyl]amino}nicotinic acid-13C6; N-(3-Trifluoromethylphenyl)anthranilic acid-13C6; R-368C-13C6; UP 83-13C6; JDL-101-13C6; Niflumic Acid (13C6); [13C6]-Niflumic Acid
EINECS	Contact for details

Quality Control

Our Niflumic Acid-13C6 is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity for demanding analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC), and confirmation of structure (by NMR and MS). We support compliance with GMP/GLP guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity	≥99 atom % 13C
Chemical Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.