Description

Mapenterol-D11 Hydrochloride is a high-purity, deuterium-labeled internal standard critical for advanced analytical quantification. This compound is essential for ensuring accuracy and reliability in sensitive mass spectrometry-based analyses, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities requiring precise deuterated standards for method development and validation.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in bioanalytical methods for the accurate measurement of Mapenterol and its metabolites in biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK): Facilitates precise studies on absorption, distribution, metabolism, and excretion (ADME) of the parent drug candidate.
• Clinical Trial Support: Enables reliable drug concentration monitoring in plasma, serum, and urine samples during clinical phases.
• Forensic and Anti-Doping Analysis: Serves as a critical component in confirmatory testing protocols where high specificity and accuracy are mandated.
• Pharmaceutical Quality Control: Supports impurity profiling and stability-indicating assay methods for drug substance and product analysis.

Basic Information

Product Name	Mapenterol-D11 Hydrochloride
CAS No.	1325559-18-9
Molecular Formula	C19H15D11Cl2N2O3 • HCl
Molecular Weight	~455.9 g/mol (for monoisotopic)
Synonyms	Mapenterol-d11 HCl; 8-Hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone-d11 Hydrochloride; (R,R)-Formoterol-d11 Hydrochloride; Formoterol-d11 Fumarate (related salt); AR-Formoterol-d11 HCl; (R,R)-Formoterol D11 Hydrochloride; 3-Formylamino-4-hydroxy-α-[[[2-(4-methoxyphenyl)-1-methylethyl]amino]methyl]benzenemethanol-d11 Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Mapenterol-D11 Hydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment. Our quality system is designed to meet the exacting requirements of analytical reference standard applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, isotopic purity, chemical purity, and related substances by HPLC and/or LC-MS.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98.0 atom % D
Chemical Purity (HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.