Description

n-(4-Methoxybenzyl) 1-Boc-Piperidine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine carboxylic acid scaffold. This compound is critical for medicinal chemistry research and development, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and metabolic disorder treatments.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile, protected amine and amide functionalities.
• Peptidomimetic Synthesis: Acts as a constrained amino acid surrogate in the design and construction of peptide-like molecules to enhance metabolic stability.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	n-(4-Methoxybenzyl) 1-Boc-Piperidine-3-Carboxamide
CAS No.	1324180-15-5
Molecular Formula	C19H28N2O4
Molecular Weight	348.44 g/mol
Synonyms	1-Boc-3-[(4-Methoxybenzyl)carbamoyl]piperidine; tert-Butyl 3-{[(4-methoxyphenyl)methyl]carbamoyl}piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid (4-methoxybenzyl)amide; N-(4-Methoxybenzyl)-1-Boc-piperidine-3-carboxamide; 1-Boc-Piperidine-3-Carboxylic Acid (4-Methoxy-benzyl)-amide; BOC-PIPERIDINE-3-CARBOXYLIC ACID (4-METHOXY-BENZYL)-AMIDE; 1324180-15-5
EINECS	Contact for details

Quality Control

Our n-(4-Methoxybenzyl) 1-Boc-Piperidine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.