Description

4-Chloro-2-Fluoro-3-Methoxyphenylacetonitrile, 97% is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique halogenated and methoxylated structure, which provides distinct reactivity for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a crucial precursor for manufacturing advanced herbicides, fungicides, and insecticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity.
• Ligand and Catalyst Development: Used in organic and organometallic chemistry research to create specialized ligands for catalysis and material science applications.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials due to its aromatic core and nitrile functionality.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Chloro-2-Fluoro-3-Methoxyphenylacetonitrile, 97%
CAS No.	1323966-29-5
Molecular Formula	C9H7ClFNO
Molecular Weight	199.61 g/mol
Synonyms	2-(4-Chloro-2-fluoro-3-methoxyphenyl)acetonitrile; (4-Chloro-2-fluoro-3-methoxyphenyl)acetonitrile; 4-Chloro-2-fluoro-3-methoxybenzyl cyanide; 2-Fluoro-4-chloro-3-methoxyphenylacetonitrile; 1323966-29-5; 4-Chloro-2-fluoro-3-methoxybenzenacetonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2-Fluoro-3-Methoxyphenylacetonitrile is produced and tested under a strict quality management system. We guarantee a minimum purity of 97% (typically by HPLC), with comprehensive impurity profiling to ensure consistency and reliability for your synthetic processes. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.