Description

4-Chloro-3-Ethoxy-2-Fluorophenylacetic Acid, 97% is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the specific substitution pattern can impart unique biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the fluorine and chlorine substituents for enhanced efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated aromatic cores used in electronic materials, contributing to improved performance in display technologies.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic & Industrial R&D: A valuable reagent for methodological studies in cross-coupling reactions, fluorination chemistry, and the exploration of new chemical spaces.

Basic Information

Product Name	4-Chloro-3-Ethoxy-2-Fluorophenylacetic Acid, 97%
CAS No.	1323955-63-0
Molecular Formula	C₁₀H₁₀ClFO₃
Molecular Weight	232.64 g/mol
Synonyms	2-(4-Chloro-3-ethoxy-2-fluorophenyl)acetic Acid; 4-Chloro-3-ethoxy-2-fluorobenzeneacetic Acid; (4-Chloro-3-ethoxy-2-fluorophenyl)acetic Acid; 2-Fluoro-4-chloro-3-ethoxyphenylacetic Acid; α-(4-Chloro-3-ethoxy-2-fluorophenyl)acetic Acid; 1323955-63-0; 4-Chloro-3-ethoxy-2-fluorophenylacetic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Ethoxy-2-Fluorophenylacetic Acid is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.