Description

4-Hydroxy Mepivacaine-D3 is a deuterated analog of the primary metabolite of the local anesthetic Mepivacaine. This stable isotope-labeled compound is essential for precise analytical quantification and metabolic studies, ensuring accurate and reliable data in research and development. It is primarily used by pharmaceutical researchers, analytical laboratories, and contract research organizations (CROs) engaged in pharmacokinetic studies, bioanalytical method development, and drug metabolism and safety testing.

Application

• Internal Standard for LC-MS/MS Analysis: Serves as a critical reference standard for the accurate quantification of Mepivacaine and its metabolites in biological matrices like plasma, serum, and urine.
• Pharmacokinetic and Bioavailability Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in clinical and preclinical research.
• Drug Metabolism Research: Used to elucidate metabolic pathways and identify specific metabolites of Mepivacaine, aiding in drug safety and efficacy profiling.
• Forensic and Clinical Toxicology: Supports the development and validation of highly specific and sensitive assays for detecting and quantifying Mepivacaine in forensic and diagnostic applications.
• Quality Control in Pharmaceutical Manufacturing: Acts as a reference material for ensuring the consistency and purity of Mepivacaine-based pharmaceutical products.

Basic Information

Product Name	4-Hydroxy Mepivacaine-D3
CAS No.	1323251-06-4
Molecular Formula	C15H19D3N2O2
Molecular Weight	265.37 g/mol (approx.)
Synonyms	1-Methyl-2',6'-pipecoloxylidide-4-ol-D3; 4'-Hydroxy Mepivacaine-D3; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide-4-ol-D3; Mepivacaine Hydroxy Metabolite-D3; Mepivacaine 4-Hydroxy Metabolite-D3; 4-OH Mepivacaine-D3; Deuterated 4-Hydroxy Mepivacaine
EINECS	Contact for details

Quality Control

Our 4-Hydroxy Mepivacaine-D3 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch undergoes comprehensive testing, including HPLC for chemical purity and MS for isotopic enrichment verification. A detailed Certificate of Analysis (COA) is provided, documenting the exact specifications for your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.