Description

Tricyclo[3.3.1.13,7]Decane-1-Butanamide, n-[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethyl]-α-Methyl-, (αr)- is a high-purity, synthetically derived specialty chemical featuring a complex adamantane-derived core structure with a functionalized polyether side chain terminated by a reactive chloro group. This compound is engineered to serve as a versatile and critical building block in advanced organic synthesis, offering unique steric and electronic properties. It is primarily utilized by research and development teams in the pharmaceutical and advanced materials sectors for the creation of novel active pharmaceutical ingredients (APIs), polymers, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for synthesizing specialty polymers with enhanced thermal stability and specific mechanical properties.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs) due to its rigid adamantane backbone and modifiable side chain.
• Surface Modification: Employed to create functionalized surfaces on materials for biomedical devices or sensors, leveraging the reactive chloro group for further conjugation.
• Advanced Material Research: A valuable reagent in R&D for developing novel liquid crystals, dendrimers, and other nanostructured materials.

Basic Information

Product Name	Tricyclo[3.3.1.13,7]Decane-1-Butanamide, n-[2-[2-[(6-Chlorohexyl)Oxy]Ethoxy]Ethyl]-α-Methyl-, (αr)-
CAS No.	1323151-45-6
Molecular Formula	C25H44ClNO3
Molecular Weight	466.08 g/mol
Synonyms	(αR)-N-[2-[2-[(6-Chlorohexyl)oxy]ethoxy]ethyl]-α-methyl-1-adamantaneacetamide; (R)-N-(2-(2-(6-Chlorohexyloxy)ethoxy)ethyl)-2-(adamantan-1-yl)propanamide; 1-Adamantaneacetamide, N-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethyl]-α-methyl-, (αR)-; Adamantane-based chloro-polyether amide; AR-Chlorohexyloxy Adamantane Acetamide; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of this specialty intermediate adheres to strict cGMP and ISO 9001 quality management principles to ensure batch-to-batch consistency and traceability. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.