Description

Sodium:(2S,5R)-6,6-Dideuterio-3-Methyl-4,4,7-Trioxo-3-(Trideuteriomethyl)-4$L^{6}-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate is a high-purity, deuterium-labeled sodium salt of a β-lactam derivative, specifically designed for advanced research and analytical applications. This compound matters as a critical stable isotope-labeled internal standard, enabling precise quantification and metabolic studies in complex biological matrices. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) research, bioanalytical method development, and high-end chemical synthesis.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard in quantitative bioanalysis (e.g., plasma, serum) to ensure accuracy and precision in mass spectrometry.
• Drug Metabolism Studies (DMPK): Facilitates the tracking and quantification of parent drugs and metabolites in preclinical and clinical research.
• Pharmaceutical R&D: Serves as a key reagent in the development and validation of analytical methods for novel β-lactam based pharmaceuticals.
• Stable Isotope Labeling: Employed in chemical synthesis and research where deuterium labeling is required for mechanistic studies or to create labeled analogs.
• Reference Standard: Acts as a certified reference material for quality control and regulatory submissions to agencies like the FDA and EMA.

Basic Information

Item	Detail
Product Name	Sodium:(2S,5R)-6,6-Dideuterio-3-Methyl-4,4,7-Trioxo-3-(Trideuteriomethyl)-4$L^{6}-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate
CAS No.	1322625-44-4
Molecular Formula	C9H5D5NNaO5S
Molecular Weight	Contact for details
Synonyms	Sodium 6,6-dideutero-3-methyl-7-oxo-3-(trideuteriomethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide; Deuterated Sodium Clavulanate-d5; Sodium Clavulanate-d5; (2S,5R)-6,6-Dideuterio-3-Methyl-4,4,7-Trioxo-3-(Trideuteriomethyl)-4λ6-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate Sodium Salt; Clavulanic Acid-d5 Sodium Salt; Sodium Clavulanate Deuterated; β-lactamase Inhibitor-d5 Sodium Salt
EINECS	Contact for details

Quality Control

Our deuterium-labeled compounds are manufactured under strict quality systems to ensure isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment (D-content), and impurity profiles via HPLC, NMR, and MS. We adhere to relevant ICH guidelines for analytical validation. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Isotopic Purity (MS)	≥98.0 atom % D
Chemical Purity (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.