Description

(3Ar,4S,7R,7As)-2-{(1R,2S)-2-[4-(1,2-Benzisothiazol-3-Yl)Piperazin-1-Ylmethyl]Cyclohexylmethyl}Hexahydro-4,7-Methano-2H-Isoindole-1,3-Dione Hydrochloride is a high-purity, complex organic salt designed for advanced research and development. This compound is of significant interest in pharmaceutical chemistry due to its intricate molecular architecture, which incorporates a benzisothiazole-piperazine pharmacophore. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries. The material serves as a critical intermediate or reference standard in the synthesis and optimization of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a reference compound or starting material for structure-activity relationship (SAR) studies and lead optimization.
• Process Development: Serves as a critical standard for developing and scaling up synthetic routes in Active Pharmaceutical Ingredient (API) manufacturing.
• Analytical Reference Standard: High-purity grade is essential for method development, validation, and quality control (HPLC, LC-MS) in analytical laboratories.
• Biochemical Research: Potential tool compound for investigating specific biological pathways and receptor interactions in vitro.

Basic Information

Product Name	(3Ar,4S,7R,7As)-2-{(1R,2S)-2-[4-(1,2-Benzisothiazol-3-Yl)Piperazin-1-Ylmethyl]Cyclohexylmethyl}Hexahydro-4,7-Methano-2H-Isoindole-1,3-Dione Hydrochloride
CAS No.	1318074-18-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(3aR,4S,7R,7aS)-2-{[(1R,2S)-2-{[4-(1,2-Benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl]methyl}hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride; Hexahydro-4,7-methano-2H-isoindole-1,3-dione derivative hydrochloride; Benzisothiazolylpiperazine cyclohexylmethyl isoindoledione hydrochloride; CAS 1318074-18-8
EINECS	Contact for details

Quality Control

Our (3Ar,4S,7R,7As)-2-{(1R,2S)-2-[4-(1,2-Benzisothiazol-3-Yl)Piperazin-1-Ylmethyl]Cyclohexylmethyl}Hexahydro-4,7-Methano-2H-Isoindole-1,3-Dione Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.