Description

Cefoxitin-D3 Sodium Salt is a deuterium-labeled isotopologue of the second-generation cephamycin antibiotic, cefoxitin sodium. This high-purity reference standard is critical for ensuring analytical accuracy and reliability in quantitative mass spectrometry. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities for applications requiring precise internal standardization.

Application

• Used as an internal standard for the accurate quantification of cefoxitin in biological matrices via LC-MS/MS.
• Essential in pharmacokinetic and bioequivalence studies to determine drug concentration profiles.
• Supports drug metabolism and disposition (DMPK) research in preclinical and clinical development.
• Facilitates method development and validation in regulatory-compliant analytical laboratories.
• Enables quality control testing of pharmaceutical products containing cefoxitin.
• Applied in forensic and anti-doping analysis for the definitive identification of the compound.

Basic Information

Product Name	Cefoxitin-D3 Sodium Salt
CAS No.	1316289-46-9
Molecular Formula	C16H14D3N3NaO7S2
Molecular Weight	449.46 g/mol (for labeled form)
Synonyms	(3S,6R,7R,8R)-7-[[(2R,3S)-3-Carboxy-2,3,3-trideuterio-1-oxobutyl]amino]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt; Sodium (6R,7S)-3-(carbamoyloxymethyl)-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate-d3; Cefoxitin Sodium-d3; Mefoxin-d3 Sodium Salt; Cefoxitin (methyl-d3) Sodium Salt
EINECS	Contact for details

Quality Control

Our Cefoxitin-D3 Sodium Salt is manufactured under strict quality systems to ensure the high chemical purity and isotopic enrichment required for analytical reference standards. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for identity, purity (HPLC), isotopic purity (NMR/MS), and other critical parameters. We adhere to relevant ISO guidelines to guarantee product consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99.0 atom % D
Chemical Purity	≥ 95.0% (by NMR)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.