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[2-Fluoro-3-(Methoxycarbonyl)Phenyl]Boronic Acid CAS NO 1315476-07-3


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CAS No.:1315476-07-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[2-Fluoro-3-(Methoxycarbonyl)Phenyl]Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific fluorinated biaryl motifs.
  • Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
  • Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
  • Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for studying biological processes and target engagement.
  • Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D pipelines.

Basic Information

Product Name [2-Fluoro-3-(Methoxycarbonyl)Phenyl]Boronic Acid
CAS No. 1315476-07-3
Molecular Formula C9H8BFO4
Molecular Weight 197.97 g/mol
Synonyms (2-Fluoro-3-(methoxycarbonyl)phenyl)boronic acid; 3-Carbomethoxy-2-fluorophenylboronic acid; 2-Fluoro-3-methoxycarbonylbenzeneboronic acid; Methyl 2-fluoro-3-boronobenzoate; Boronic acid, B-[2-fluoro-3-(methoxycarbonyl)phenyl]-; (2-Fluoro-3-methoxycarbonylphenyl)boronic acid
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Quality Control

Our [2-Fluoro-3-(Methoxycarbonyl)Phenyl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0% (Typical 98-99%)
Water Content (KF) ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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