Description

Fmoc-α-Me-Orn(Boc)-Oh is a protected, non-proteinogenic amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound matters because it provides critical orthogonality for the controlled assembly of complex peptides, enabling the introduction of modified ornithine residues with precise stereochemistry. Pharmaceutical researchers and fine chemical manufacturers need it for the development of novel peptide-based therapeutics, diagnostic agents, and biochemical tools where structural precision is paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the controlled, sequential assembly of complex peptide chains on resin.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based drugs, including antimicrobial peptides (AMPs) and hormone analogs.
• Bioconjugation & Probe Development: Facilitates the site-specific modification of peptides for creating labeled probes used in diagnostics and imaging.
• Chemical Biology Research: Enables the study of protein-protein interactions and enzyme mechanisms by incorporating non-natural amino acids into peptide sequences.
• Material Science: Serves as a precursor for designing peptide-based biomaterials and hydrogels with tailored properties.

Basic Information

Product Name	Fmoc-α-Me-Orn(Boc)-Oh
CAS No.	1315449-95-6
Molecular Formula	C₂₆H₃₂N₂O₆
Molecular Weight	468.55 g/mol
Synonyms	Fmoc-α-Methylornithine(Boc)-OH; N-α-Fmoc-N-δ-Boc-α-methylornithine; Fmoc-(α-Me)Orn(Boc)-OH; (2S)-5-{[(2-Methylpropan-2-yl)oxy]carbonyl}amino-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methylpentanoic acid; Nδ-Boc-Nα-Fmoc-α-methyl-L-ornithine; Fmoc-α-Me-Orn(Boc)-OH; Protected α-Methylornithine derivative; Fmoc-L-α-methylornithine(Boc)-OH
EINECS	Contact for details

Quality Control

Our Fmoc-α-Me-Orn(Boc)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific GMP or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.